Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders

Many adult stem cell communities are maintained by population asymmetry, where stochastic behaviors of multiple individual cells collectively result in a balance between stem cell division and differentiation. We investigated how this is achieved for Drosophila Follicle Stem Cells (FSCs) by spatiall...

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Detalles Bibliográficos
Autores principales: Melamed, David, Kalderon, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695452/
https://www.ncbi.nlm.nih.gov/pubmed/33135631
http://dx.doi.org/10.7554/eLife.61204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695452/
https://www.ncbi.nlm.nih.gov/pubmed/33135631
http://dx.doi.org/10.7554/eLife.61204

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