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Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders
Many adult stem cell communities are maintained by population asymmetry, where stochastic behaviors of multiple individual cells collectively result in a balance between stem cell division and differentiation. We investigated how this is achieved for Drosophila Follicle Stem Cells (FSCs) by spatiall...
Autores principales: | Melamed, David, Kalderon, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695452/ https://www.ncbi.nlm.nih.gov/pubmed/33135631 http://dx.doi.org/10.7554/eLife.61204 |
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