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Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length

Displacement loops (D-loops) are critical intermediates formed during homologous recombination. Rdh54 (a.k.a. Tid1), a Rad54 paralog in Saccharomyces cerevisiae, is well-known for its role with Dmc1 recombinase during meiotic recombination. Yet contrary to Dmc1, Rdh54/Tid1 is also present in somatic...

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Detalles Bibliográficos
Autores principales: Shah, Shanaya Shital, Hartono, Stella, Piazza, Aurèle, Som, Vanessa, Wright, William, Chédin, Frédéric, Heyer, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695457/
https://www.ncbi.nlm.nih.gov/pubmed/33185188
http://dx.doi.org/10.7554/eLife.59112