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Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution

Displacement loops (D-loops) are signature intermediates formed during homologous recombination. Numerous factors regulate D-loop formation and disruption, thereby influencing crucial aspects of DNA repair, including donor choice and the possibility of crossover outcome. While D-loop detection metho...

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Detalles Bibliográficos
Autores principales: Shah, Shanaya Shital, Hartono, Stella R, Chédin, Frédéric, Heyer, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695462/
https://www.ncbi.nlm.nih.gov/pubmed/33185185
http://dx.doi.org/10.7554/eLife.59111