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Retracing the evolutionary emergence of thymopoiesis

The onset of lymphocyte development in the vertebrate primordial thymus, about 500 million years ago, represents one of the foundational events of the emerging adaptive immune system. Here, we retrace the evolutionary trajectory of thymopoiesis, from early vertebrates to mammals, guided by members o...

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Detalles Bibliográficos
Autores principales: Swann, Jeremy B., Nusser, Anja, Morimoto, Ryo, Nagakubo, Daisuke, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695478/
https://www.ncbi.nlm.nih.gov/pubmed/33246964
http://dx.doi.org/10.1126/sciadv.abd9585