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On the shuttling across the blood-brain barrier via tubule formation: Mechanism and cargo avidity bias

The blood-brain barrier is made of polarized brain endothelial cells (BECs) phenotypically conditioned by the central nervous system (CNS). Although transport across BECs is of paramount importance for nutrient uptake as well as ridding the brain of waste products, the intracellular sorting mechanis...

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Detalles Bibliográficos
Autores principales: Tian, Xiaohe, Leite, Diana M., Scarpa, Edoardo, Nyberg, Sophie, Fullstone, Gavin, Forth, Joe, Matias, Diana, Apriceno, Azzurra, Poma, Alessandro, Duro-Castano, Aroa, Vuyyuru, Manish, Harker-Kirschneck, Lena, Šarić, Anđela, Zhang, Zhongping, Xiang, Pan, Fang, Bin, Tian, Yupeng, Luo, Lei, Rizzello, Loris, Battaglia, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695481/
https://www.ncbi.nlm.nih.gov/pubmed/33246953
http://dx.doi.org/10.1126/sciadv.abc4397