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Berberine Down-Regulated Myostatin Expression and Facilitated Metabolism via Smad Pathway in Insulin Resistant Mice

OBJECTIVE: To explore the effect of berberine (BBR) on skeletal muscle mass and metabolism and the possible mechanism. METHODS: Eight-week-old male C57BL/6 mice were fed with a high-fat diet (HFD) for 8 weeks to establish the insulin resistance obesity model. Then, mice were randomly divided into tw...

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Detalles Bibliográficos
Autores principales: Chen, Lingyan, Su, Xiaojuan, Hu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695611/
https://www.ncbi.nlm.nih.gov/pubmed/33262628
http://dx.doi.org/10.2147/DMSO.S275301