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Hematopoietic stem cells from pluripotent stem cells: Clinical potential, challenges, and future perspectives

The generation of hematopoietic stem cells (HSCs) from induced pluripotent stem cells (iPSCs) is an active and promising area of research; however, generating engraftable HSCs remains a major obstacle. Ex vivo HSC derivation from renewable sources such as iPSCs offers an experimental tool for studyi...

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Detalles Bibliográficos
Autores principales: Demirci, Selami, Leonard, Alexis, Tisdale, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695636/
https://www.ncbi.nlm.nih.gov/pubmed/32725882
http://dx.doi.org/10.1002/sctm.20-0247