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A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

The independent effects of smoking and alcohol in head and neck cancer are not clear, given the strong association between these risk factors. Their apparent synergistic effect reported in previous observational studies may also underestimate independent effects. Here we report multivariable Mendeli...

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Detalles Bibliográficos
Autores principales: Gormley, Mark, Dudding, Tom, Sanderson, Eleanor, Martin, Richard M., Thomas, Steven, Tyrrell, Jessica, Ness, Andrew R., Brennan, Paul, Munafò, Marcus, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F., Diergaarde, Brenda, Hung, Rayjean J., Liu, Geoffrey, Davey Smith, George, Richmond, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695733/
https://www.ncbi.nlm.nih.gov/pubmed/33247085
http://dx.doi.org/10.1038/s41467-020-19822-6