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A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer
The independent effects of smoking and alcohol in head and neck cancer are not clear, given the strong association between these risk factors. Their apparent synergistic effect reported in previous observational studies may also underestimate independent effects. Here we report multivariable Mendeli...
Autores principales: | Gormley, Mark, Dudding, Tom, Sanderson, Eleanor, Martin, Richard M., Thomas, Steven, Tyrrell, Jessica, Ness, Andrew R., Brennan, Paul, Munafò, Marcus, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F., Diergaarde, Brenda, Hung, Rayjean J., Liu, Geoffrey, Davey Smith, George, Richmond, Rebecca C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695733/ https://www.ncbi.nlm.nih.gov/pubmed/33247085 http://dx.doi.org/10.1038/s41467-020-19822-6 |
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