In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo

Engineering chimeric antigen receptors (CAR) or T cell receptors (TCR) helps create disease-specific T cells for targeted therapy, but the cost and rigor associated with manufacturing engineered T cells ex vivo can be prohibitive, so programing T cells in vivo may be a viable alternative. Here we re...

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Detalles Bibliográficos
Autores principales: Parayath, N. N., Stephan, S. B., Koehne, A. L., Nelson, P. S., Stephan, M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695830/
https://www.ncbi.nlm.nih.gov/pubmed/33247092
http://dx.doi.org/10.1038/s41467-020-19486-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695830/
https://www.ncbi.nlm.nih.gov/pubmed/33247092
http://dx.doi.org/10.1038/s41467-020-19486-2

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