Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

To study the localisation of G protein-coupled receptors (GPCR) in their native cellular environment requires their visualisation through fluorescent labelling. To overcome the requirement for genetic modification of the receptor or the limitations of dissociable fluorescent ligands, here we describ...

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Detalles Bibliográficos
Autores principales: Stoddart, Leigh A., Kindon, Nicholas D., Otun, Omolade, Harwood, Clare R., Patera, Foteini, Veprintsev, Dmitry B., Woolard, Jeanette, Briddon, Stephen J., Franks, Hester A., Hill, Stephen J., Kellam, Barrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695831/
https://www.ncbi.nlm.nih.gov/pubmed/33247190
http://dx.doi.org/10.1038/s42003-020-01451-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695831/
https://www.ncbi.nlm.nih.gov/pubmed/33247190
http://dx.doi.org/10.1038/s42003-020-01451-w

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