Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war

Catalysis of cis/trans isomerization of prolines is important for the activity and misfolding of intrinsically disordered proteins. Catalysis is achieved by peptidylprolyl isomerases, a superfamily of molecular chaperones. Here, we provide atomic insight into a tug-of-war between cis/trans isomeriza...

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Detalles Bibliográficos
Autores principales: Favretto, Filippo, Flores, David, Baker, Jeremy D., Strohäker, Timo, Andreas, Loren B., Blair, Laura J., Becker, Stefan, Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695863/
https://www.ncbi.nlm.nih.gov/pubmed/33247146
http://dx.doi.org/10.1038/s41467-020-19844-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695863/
https://www.ncbi.nlm.nih.gov/pubmed/33247146
http://dx.doi.org/10.1038/s41467-020-19844-0

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