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Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war
Catalysis of cis/trans isomerization of prolines is important for the activity and misfolding of intrinsically disordered proteins. Catalysis is achieved by peptidylprolyl isomerases, a superfamily of molecular chaperones. Here, we provide atomic insight into a tug-of-war between cis/trans isomeriza...
Autores principales: | Favretto, Filippo, Flores, David, Baker, Jeremy D., Strohäker, Timo, Andreas, Loren B., Blair, Laura J., Becker, Stefan, Zweckstetter, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695863/ https://www.ncbi.nlm.nih.gov/pubmed/33247146 http://dx.doi.org/10.1038/s41467-020-19844-0 |
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