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New luciferin-based probe substrates for human CYP26A1

Activity of human CYP26A1 towards six proluciferin probe substrates and their ester derivatives was monitored. These included three monofluorobenzyl ether isomers and three five-membered heterocycles. Overall, luciferin substrates with a free acid group gave higher activities than the ester compound...

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Detalles Bibliográficos
Autores principales: Sharma, Shishir, Liu, Jingyao, Zhang, Xue, Sharma, Sangeeta Shrestha, Sorensen, Erik J., Bureik, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695906/
https://www.ncbi.nlm.nih.gov/pubmed/33294638
http://dx.doi.org/10.1016/j.bbrep.2020.100861