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Extended transcriptome analysis reveals genome-wide lncRNA-mediated epigenetic dysregulation in colorectal cancer

It is estimated that the rate of epigenetic changes may be orders of magnitude higher than that of genetic changes and that purely epigenetic mechanisms may explain why cancers arise with few or no recurrent mutations. However, supporting evidence remains limited, partly due to the cost of experimen...

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Detalles Bibliográficos
Autores principales: He, Sha, Chen, Juanzhi, Gao, Huan, Yang, Guixian, Zhang, Feixiang, Ding, Yanqing, Zhu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695927/
https://www.ncbi.nlm.nih.gov/pubmed/33304451
http://dx.doi.org/10.1016/j.csbj.2020.11.004