Cargando…

Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival

Increased expression of Yes-associated protein-1 (YAP1) was shown to correlate with reduced survival in breast cancer (BC) patients. However, the exact mechanism of YAP1 regulation in BC cells remains ambiguous. Genomic sequence search showed that the promoter region of the YAP1 gene contains CpG Is...

Descripción completa

Detalles Bibliográficos
Autores principales: Muhammad, Jibran Sualeh, Guimei, Maha, Jayakumar, Manju Nidagodu, Shafarin, Jasmin, Janeeh, Aisha Saleh, AbuJabal, Rola, Eladl, Mohamed Ahmed, Ranade, Anu Vinod, Ali, Amjad, Hamad, Mawieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695929/
https://www.ncbi.nlm.nih.gov/pubmed/33242831
http://dx.doi.org/10.1016/j.neo.2020.11.002