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Evidence for liver and peripheral immune cells secreting tumor-suppressive extracellular vesicles in melanoma patients

BACKGROUND: Before and after surgery melanoma patients harbor elevated levels of extracellular vesicles in plasma (pEV), suppressing tumor cell activity. However, due to technical reasons and lack of cell-specific biomarkers, their cellular origin remains obscure. METHODS: We mimicked the interactio...

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Detalles Bibliográficos
Autores principales: Lee, Jung-Hyun, Eberhardt, Martin, Blume, Katja, Vera, Julio, Baur, Andreas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695971/
https://www.ncbi.nlm.nih.gov/pubmed/33242827
http://dx.doi.org/10.1016/j.ebiom.2020.103119