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Reductive stress promotes protein aggregation and impairs neurogenesis

Redox homeostasis regulates key cellular signaling in both physiology and pathology. While perturbations result in shifting the redox homeostasis towards oxidative stress are well documented, the influence of reductive stress (RS) in neurodegenerative diseases and its mechanisms are unknown. Here, w...

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Detalles Bibliográficos
Autores principales: S Narasimhan, Kishore Kumar, Devarajan, Asokan, Karan, Goutam, Sundaram, Sandhya, Wang, Qin, van Groen, Thomas, Monte, Federica del, Rajasekaran, Namakkal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695986/
https://www.ncbi.nlm.nih.gov/pubmed/33242767
http://dx.doi.org/10.1016/j.redox.2020.101739