Cargando…
Reductive stress promotes protein aggregation and impairs neurogenesis
Redox homeostasis regulates key cellular signaling in both physiology and pathology. While perturbations result in shifting the redox homeostasis towards oxidative stress are well documented, the influence of reductive stress (RS) in neurodegenerative diseases and its mechanisms are unknown. Here, w...
Autores principales: | S Narasimhan, Kishore Kumar, Devarajan, Asokan, Karan, Goutam, Sundaram, Sandhya, Wang, Qin, van Groen, Thomas, Monte, Federica del, Rajasekaran, Namakkal S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695986/ https://www.ncbi.nlm.nih.gov/pubmed/33242767 http://dx.doi.org/10.1016/j.redox.2020.101739 |
Ejemplares similares
-
Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress
por: Kumar, Radhakrishnan Rajesh, et al.
Publicado: (2016) -
Reductive stress impairs myogenic differentiation
por: Rajasekaran, Namakkal S., et al.
Publicado: (2020) -
Exercise, Nrf2 and Antioxidant Signaling in Cardiac Aging
por: Narasimhan, Madhusudhanan, et al.
Publicado: (2016) -
Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium
por: Shanmugam, Gobinath, et al.
Publicado: (2017) -
Identification of transcriptome signature for myocardial reductive stress
por: Quiles, Justin M., et al.
Publicado: (2017)