Phased Haplotype Resolution of the SLC6A4 Promoter Using Long-Read Single Molecule Real-Time (SMRT) Sequencing

The SLC6A4 gene has been implicated in psychiatric disorder susceptibility and antidepressant response variability. The SLC6A4 promoter is defined by a variable number of homologous 20–24 bp repeats (5-HTTLPR), and long (L) and short (S) alleles are associated with higher and lower expression, respe...

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Detalles Bibliográficos
Autores principales: Botton, Mariana R., Yang, Yao, Scott, Erick R., Desnick, Robert J., Scott, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696006/
https://www.ncbi.nlm.nih.gov/pubmed/33198140
http://dx.doi.org/10.3390/genes11111333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696006/
https://www.ncbi.nlm.nih.gov/pubmed/33198140
http://dx.doi.org/10.3390/genes11111333

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