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p62-Nrf2-p62 Mitophagy Regulatory Loop as a Target for Preventive Therapy of Neurodegenerative Diseases

Turnover of the mitochondrial pool due to coordinated processes of mitochondrial biogenesis and mitophagy is an important process in maintaining mitochondrial stability. An important role in this process is played by the Nrf2/ARE signaling pathway, which is involved in the regulation of the expressi...

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Detalles Bibliográficos
Autores principales: Gureev, Artem P., Sadovnikova, Irina S., Starkova, Natalia N., Starkov, Anatoly A., Popov, Vasily N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696015/
https://www.ncbi.nlm.nih.gov/pubmed/33198234
http://dx.doi.org/10.3390/brainsci10110847