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Reducing the Number of Mismatches between Hairs and Buccal References When Analysing mtDNA Heteroplasmic Variation by Massively Parallel Sequencing

In forensics, mitochondrial DNA (mtDNA) analysis is foremost applied to rootless hairs often lacking detectable nuclear DNA. Sanger sequencing is the routine mtDNA method in most forensic laboratories, even though interpretation of mixed samples and heteroplasmic sites can be challenging. Individual...

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Detalles Bibliográficos
Autores principales: van der Gaag, Kristiaan J., Desmyter, Stijn, Smit, Sophie, Prieto, Lourdes, Sijen, Titia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696041/
https://www.ncbi.nlm.nih.gov/pubmed/33207560
http://dx.doi.org/10.3390/genes11111355