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Reducing the Number of Mismatches between Hairs and Buccal References When Analysing mtDNA Heteroplasmic Variation by Massively Parallel Sequencing
In forensics, mitochondrial DNA (mtDNA) analysis is foremost applied to rootless hairs often lacking detectable nuclear DNA. Sanger sequencing is the routine mtDNA method in most forensic laboratories, even though interpretation of mixed samples and heteroplasmic sites can be challenging. Individual...
Autores principales: | van der Gaag, Kristiaan J., Desmyter, Stijn, Smit, Sophie, Prieto, Lourdes, Sijen, Titia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696041/ https://www.ncbi.nlm.nih.gov/pubmed/33207560 http://dx.doi.org/10.3390/genes11111355 |
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