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Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8(+) T Cells in Non-Melanoma Cancers Compared to Melanoma

SIMPLE SUMMARY: Human tumors are often infiltrated by T cells; however, it remains unclear what proportion of T cells infiltrating tumors are bystander and non-tumor specific. We have investigated qualitative characteristics of these tumor-infiltrating lymphocytes (TILs) based on their gene-expressi...

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Detalles Bibliográficos
Autores principales: Gokuldass, Aishwarya, Draghi, Arianna, Papp, Krisztian, Borch, Troels Holz, Nielsen, Morten, Westergaard, Marie Christine Wulff, Andersen, Rikke, Schina, Aimilia, Bol, Kalijn Fredrike, Chamberlain, Christopher Aled, Presti, Mario, Met, Özcan, Harbst, Katja, Lauss, Martin, Soraggi, Samuele, Csabai, Istvan, Szállási, Zoltán, Jönsson, Göran, Svane, Inge Marie, Donia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696049/
https://www.ncbi.nlm.nih.gov/pubmed/33198174
http://dx.doi.org/10.3390/cancers12113344