Evaluation of Actinium-225 Labeled Minigastrin Analogue [(225)Ac]Ac-DOTA-PP-F11N for Targeted Alpha Particle Therapy

The overexpression of cholecystokinin B receptor (CCKBR) in human cancers led to the development of radiolabeled minigastrin analogues for targeted radionuclide therapy, which aims to deliver cytotoxic radiation specifically to cancer cells. Alpha emitters (e.g., actinium-225) possess high potency i...

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Detalles Bibliográficos
Autores principales: Qin, Yun, Imobersteg, Stefan, Blanc, Alain, Frank, Stephan, Schibli, Roger, Béhé, Martin P., Grzmil, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696055/
https://www.ncbi.nlm.nih.gov/pubmed/33198403
http://dx.doi.org/10.3390/pharmaceutics12111088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696055/
https://www.ncbi.nlm.nih.gov/pubmed/33198403
http://dx.doi.org/10.3390/pharmaceutics12111088

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