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The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment

SIMPLE SUMMARY: The unique characteristics of tumor energy metabolism (highly dependent on aerobic glycolysis, namely, the Warburg effect) make it an interesting and attractive target for drug discovery. Radio- and chemoresistance are closely associated with the Warburg effect. Lonidamine (LND), as...

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Detalles Bibliográficos
Autores principales: Huang, Yaxin, Sun, Guohui, Sun, Xiaodong, Li, Feifan, Zhao, Lijiao, Zhong, Rugang, Peng, Yongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696079/
https://www.ncbi.nlm.nih.gov/pubmed/33187214
http://dx.doi.org/10.3390/cancers12113332