Engineering Next-Generation CAR-T Cells for Better Toxicity Management

Immunoadoptive therapy with genetically modified T lymphocytes expressing chimeric antigen receptors (CARs) has revolutionized the treatment of patients with hematologic cancers. Although clinical outcomes in B-cell malignancies are impressive, researchers are seeking to enhance the activity, persis...

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Detalles Bibliográficos
Autores principales: Andrea, Alain E., Chiron, Andrada, Bessoles, Stéphanie, Hacein-Bey-Abina, Salima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696189/
https://www.ncbi.nlm.nih.gov/pubmed/33207607
http://dx.doi.org/10.3390/ijms21228620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696189/
https://www.ncbi.nlm.nih.gov/pubmed/33207607
http://dx.doi.org/10.3390/ijms21228620

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