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Engineering Next-Generation CAR-T Cells for Better Toxicity Management
Immunoadoptive therapy with genetically modified T lymphocytes expressing chimeric antigen receptors (CARs) has revolutionized the treatment of patients with hematologic cancers. Although clinical outcomes in B-cell malignancies are impressive, researchers are seeking to enhance the activity, persis...
Autores principales: | Andrea, Alain E., Chiron, Andrada, Bessoles, Stéphanie, Hacein-Bey-Abina, Salima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696189/ https://www.ncbi.nlm.nih.gov/pubmed/33207607 http://dx.doi.org/10.3390/ijms21228620 |
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