Bi-Functional Alginate Oligosaccharide–Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections

The recent emergence of resistance to colistin, an antibiotic of last resort with dose-limiting toxicity, has highlighted the need for alternative approaches to combat infection. This study aimed to generate and characterise alginate oligosaccharide (“OligoG”)–polymyxin (polymyxin B and E (colistin)...

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Detalles Bibliográficos
Autores principales: Stokniene, Joana, Powell, Lydia C., Aarstad, Olav A., Aachmann, Finn L., Rye, Philip D., Hill, Katja E., Thomas, David W., Ferguson, Elaine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696216/
https://www.ncbi.nlm.nih.gov/pubmed/33187332
http://dx.doi.org/10.3390/pharmaceutics12111080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696216/
https://www.ncbi.nlm.nih.gov/pubmed/33187332
http://dx.doi.org/10.3390/pharmaceutics12111080

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