In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation

Sortase A (SrtA) is a membrane-associated enzyme that anchors surface-exposed proteins to the cell wall envelope of Gram-positive bacteria such as Staphylococcus aureus. As SrtA is essential for Gram-positive bacterial pathogenesis but dispensable for microbial growth or viability, SrtA is considere...

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Detalles Bibliográficos
Autores principales: Thappeta, Kishore Reddy Venkata, Zhao, Li Na, Nge, Choy Eng, Crasta, Sharon, Leong, Chung Yan, Ng, Veronica, Kanagasundaram, Yoganathan, Fan, Hao, Ng, Siew Bee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696255/
https://www.ncbi.nlm.nih.gov/pubmed/33202690
http://dx.doi.org/10.3390/ijms21228601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696255/
https://www.ncbi.nlm.nih.gov/pubmed/33202690
http://dx.doi.org/10.3390/ijms21228601

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