Cargando…
In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation
Sortase A (SrtA) is a membrane-associated enzyme that anchors surface-exposed proteins to the cell wall envelope of Gram-positive bacteria such as Staphylococcus aureus. As SrtA is essential for Gram-positive bacterial pathogenesis but dispensable for microbial growth or viability, SrtA is considere...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696255/ https://www.ncbi.nlm.nih.gov/pubmed/33202690 http://dx.doi.org/10.3390/ijms21228601 |