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Physiological Roles of ERM Proteins and Transcriptional Regulators in Supporting Membrane Expression of Efflux Transporters as Factors of Drug Resistance in Cancer

SIMPLE SUMMARY: Multidrug resistance and infiltration/metastasis of cancer are two major issues that must be overcome during chemotherapy. Efflux transporters, such as P-glycoprotein (P-gp), multidrug resistance-associated proteins, and breast cancer resistance protein play an important role in mult...

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Detalles Bibliográficos
Autores principales: Ogihara, Takuo, Mizoi, Kenta, Kamioka, Hiroki, Yano, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696277/
https://www.ncbi.nlm.nih.gov/pubmed/33198344
http://dx.doi.org/10.3390/cancers12113352