Virtual Screening and In Vitro Evaluation of PD-1 Dimer Stabilizers for Uncoupling PD-1/PD-L1 Interaction from Natural Products

Genetic mutations accumulated overtime could generate many growth and survival advantages for cancer cells, but these mutations also mark cancer cells as targets to be eliminated by the immune system. To evade immune surveillance, cancer cells adopted different intrinsic molecules to suppress immune...

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Detalles Bibliográficos
Autores principales: Lung, Jrhau, Hung, Ming-Szu, Lin, Yu-Ching, Hung, Chien-Hui, Chen, Chih-Cheng, Lee, Kuan-Der, Tsai, Ying Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696397/
https://www.ncbi.nlm.nih.gov/pubmed/33202823
http://dx.doi.org/10.3390/molecules25225293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696397/
https://www.ncbi.nlm.nih.gov/pubmed/33202823
http://dx.doi.org/10.3390/molecules25225293

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