8-Hydroxydaidzein, an Isoflavone from Fermented Soybean, Induces Autophagy, Apoptosis, Differentiation, and Degradation of Oncoprotein BCR-ABL in K562 Cells

8-Hydroxydaidzein (8-OHD, 7,8,4′-trihydoxyisoflavone) is a hydroxylated derivative of daidzein isolated from fermented soybean products. The aim of this study is to investigate the anti-proliferative effects and the underlying mechanisms of 8-OHD in K562 human chronic myeloid leukemia (CML) cells. W...

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Detalles Bibliográficos
Autores principales: Wu, Pei-Shan, Yen, Jui-Hung, Wang, Chih-Yang, Chen, Pei-Yi, Hung, Jui-Hsiang, Wu, Ming-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696406/
https://www.ncbi.nlm.nih.gov/pubmed/33207739
http://dx.doi.org/10.3390/biomedicines8110506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696406/
https://www.ncbi.nlm.nih.gov/pubmed/33207739
http://dx.doi.org/10.3390/biomedicines8110506

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