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Increase in Epithelial Permeability and Cell Metabolism by High Mobility Group Box 1, Inflammatory Cytokines and TPEN in Caco-2 Cells as a Novel Model of Inflammatory Bowel Disease

High mobility group box 1 protein (HMGB1) is involved in the pathogenesis of inflammatory bowel disease (IBD). Patients with IBD develop zinc deficiency. However, the detailed roles of HMGB1 and zinc deficiency in the intestinal epithelial barrier and cellular metabolism of IBD remain unknown. In th...

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Detalles Bibliográficos
Autores principales: Miyakawa, Maki, Konno, Takumi, Kohno, Takayuki, Kikuchi, Shin, Tanaka, Hiroki, Kojima, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696423/
https://www.ncbi.nlm.nih.gov/pubmed/33182652
http://dx.doi.org/10.3390/ijms21228434