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Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion

Microglia, predominant parenchymal resident macrophages in the central nervous system (CNS), are crucial players in neurodevelopment and CNS homeostasis. In disease conditions, pro-inflammatory microglia predominate over their regulatory counterparts, and are thus a potential immunotherapeutic targe...

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Detalles Bibliográficos
Autores principales: Han, Jinming, Fan, Yueshan, Zhou, Kai, Zhu, Keying, Blomgren, Klas, Lund, Harald, Zhang, Xing-Mei, Harris, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696443/
https://www.ncbi.nlm.nih.gov/pubmed/33203068
http://dx.doi.org/10.3390/ijms21228603