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Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion
Microglia, predominant parenchymal resident macrophages in the central nervous system (CNS), are crucial players in neurodevelopment and CNS homeostasis. In disease conditions, pro-inflammatory microglia predominate over their regulatory counterparts, and are thus a potential immunotherapeutic targe...
Autores principales: | Han, Jinming, Fan, Yueshan, Zhou, Kai, Zhu, Keying, Blomgren, Klas, Lund, Harald, Zhang, Xing-Mei, Harris, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696443/ https://www.ncbi.nlm.nih.gov/pubmed/33203068 http://dx.doi.org/10.3390/ijms21228603 |
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