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Nox4 Facilitates TGFβ1-Induced Fibrotic Response in Human Tenon’s Fibroblasts and Promotes Wound Collagen Accumulation in Murine Model of Glaucoma Filtration Surgery

Collagen accumulation in sub-conjunctival tissue at the surgical wound is one of the major complications associated with glaucoma filtration surgery (GFS). This process often leads to unwanted fibrotic scar formation at the lesion site and dysfunction of tissues. Previously, we demonstrated that NAD...

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Detalles Bibliográficos
Autores principales: Shah, Manisha H., Chan, Elsa C., Van Bergen, Nicole J., Pandav, Surinder S., Ng, Sze, Crowston, Jonathan G., Peshavariya, Hitesh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696451/
https://www.ncbi.nlm.nih.gov/pubmed/33202904
http://dx.doi.org/10.3390/antiox9111126