Aesculetin Inhibits Osteoclastic Bone Resorption through Blocking Ruffled Border Formation and Lysosomal Trafficking

For the optimal resorption of mineralized bone matrix, osteoclasts require the generation of the ruffled border and acidic resorption lacuna through lysosomal trafficking and exocytosis. Coumarin-type aesculetin is a naturally occurring compound with anti-inflammatory and antibacterial effects. Howe...

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Detalles Bibliográficos
Autores principales: Na, Woojin, Lee, Eun-Jung, Kang, Min-Kyung, Kim, Yun-Ho, Kim, Dong Yeon, Oh, Hyeongjoo, Kim, Soo-Il, Oh, Su Yeon, Kang, Young-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696459/
https://www.ncbi.nlm.nih.gov/pubmed/33203061
http://dx.doi.org/10.3390/ijms21228581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696459/
https://www.ncbi.nlm.nih.gov/pubmed/33203061
http://dx.doi.org/10.3390/ijms21228581

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