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Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” Strategies

Primary mitochondrial diseases (PMD) refer to a group of severe, often inherited genetic conditions due to mutations in the mitochondrial genome or in the nuclear genes encoding for proteins involved in oxidative phosphorylation (OXPHOS). The mutations hamper the last step of aerobic metabolism, aff...

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Detalles Bibliográficos
Autores principales: Bottani, Emanuela, Lamperti, Costanza, Prigione, Alessandro, Tiranti, Valeria, Persico, Nicola, Brunetti, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696526/
https://www.ncbi.nlm.nih.gov/pubmed/33187380
http://dx.doi.org/10.3390/pharmaceutics12111083