Synthesis of Polyheterocyclic Dimers Containing Restricted and Constrained Peptidomimetics via IMCR-Based Domino/Double CuAAC Click Strategy

A novel strategy via the triple process (multicomponent reactions (MCR)-domino)/tandem was developed for the synthesis of restricted and constrained bis-1,2,3-triazole-linked pyrrolo[3,4-b]pyridine peptidomimetics dimers in overall yields of 20–55%. This strategy allows the construction of six heter...

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Detalles Bibliográficos
Autores principales: Pharande, Shrikant G., Rentería-Gómez, Manuel A., Gámez-Montaño, Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696539/
https://www.ncbi.nlm.nih.gov/pubmed/33187075
http://dx.doi.org/10.3390/molecules25225246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696539/
https://www.ncbi.nlm.nih.gov/pubmed/33187075
http://dx.doi.org/10.3390/molecules25225246

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