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Pharmacological Modulators of Tau Aggregation and Spreading

Tauopathies are neurodegenerative disorders characterized by the deposition of aggregates composed of abnormal tau protein in the brain. Additionally, misfolded forms of tau can propagate from cell to cell and throughout the brain. This process is thought to lead to the templated misfolding of the n...

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Detalles Bibliográficos
Autores principales: Dominguez-Meijide, Antonio, Vasili, Eftychia, Outeiro, Tiago Fleming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696562/
https://www.ncbi.nlm.nih.gov/pubmed/33203009
http://dx.doi.org/10.3390/brainsci10110858