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Generation of Cochlear Hair Cells from Sox2 Positive Supporting Cells via DNA Demethylation

Regeneration of auditory hair cells in adult mammals is challenging. It is also difficult to track the sources of regenerated hair cells, especially in vivo. Previous paper found newly generated hair cells in deafened mouse by injecting a DNA methyltransferase inhibitor 5-azacytidine into the inner...

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Detalles Bibliográficos
Autores principales: Deng, Xin, Hu, Zhengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696585/
https://www.ncbi.nlm.nih.gov/pubmed/33212773
http://dx.doi.org/10.3390/ijms21228649