Ferroptosis in Friedreich’s Ataxia: A Metal-Induced Neurodegenerative Disease

Ferroptosis is an iron-dependent form of regulated cell death, arising from the accumulation of lipid-based reactive oxygen species when glutathione-dependent repair systems are compromised. Lipid peroxidation, mitochondrial impairment and iron dyshomeostasis are the hallmark of ferroptosis, which i...

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Detalles Bibliográficos
Autores principales: La Rosa, Piergiorgio, Petrillo, Sara, Fiorenza, Maria Teresa, Bertini, Enrico Silvio, Piemonte, Fiorella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696618/
https://www.ncbi.nlm.nih.gov/pubmed/33202971
http://dx.doi.org/10.3390/biom10111551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696618/
https://www.ncbi.nlm.nih.gov/pubmed/33202971
http://dx.doi.org/10.3390/biom10111551

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