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Rhabdomyolysis-Induced AKI Was Ameliorated in NLRP3 KO Mice via Alleviation of Mitochondrial Lipid Peroxidation in Renal Tubular Cells

Introduction: A recent study showed that early renal tubular injury is ameliorated in Nod-like receptor pyrin domain-containing protein 3 (NLRP3) KO mice with rhabdomyolysis-induced acute kidney injury (RIAKI). However, the precise mechanism has not been determined. Therefore, we investigated the ro...

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Detalles Bibliográficos
Autores principales: Song, Seok Jong, Kim, Su-mi, Lee, Sang-ho, Moon, Ju-Young, Hwang, Hyeon Seok, Kim, Jin Sug, Park, Seon-Hwa, Jeong, Kyung Hwan, Kim, Yang Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696646/
https://www.ncbi.nlm.nih.gov/pubmed/33202867
http://dx.doi.org/10.3390/ijms21228564