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P2Y(2) and P2X4 Receptors Mediate Ca(2+) Mobilization in DH82 Canine Macrophage Cells

Purinergic receptors of the P2 subclass are commonly found in human and rodent macrophages where they can be activated by adenosine 5′-triphosphate (ATP) or uridine 5′-triphosphate (UTP) to mediate Ca(2+) mobilization, resulting in downstream signalling to promote inflammation and pain. However, lit...

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Detalles Bibliográficos
Autores principales: Sophocleous, Reece Andrew, Miles, Nicole Ashleigh, Ooi, Lezanne, Sluyter, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696671/
https://www.ncbi.nlm.nih.gov/pubmed/33202978
http://dx.doi.org/10.3390/ijms21228572