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IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is rising in prevalence, and a better pathophysiologic understanding of the transition to its inflammatory phenotype (NASH) is key to the development of effective therapies. To evaluate the contribution of the NLRP3 inflammasome and its downstream effectors...

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Detalles Bibliográficos
Autores principales: Hohenester, Simon, Kanitz, Veronika, Schiergens, Tobias, Einer, Claudia, Nagel, Jutta, Wimmer, Ralf, Reiter, Florian P., Gerbes, Alexander L., De Toni, Enrico N., Bauer, Christian, Holdt, Lesca, Mayr, Doris, Rust, Christian, Schnurr, Max, Zischka, Hans, Geier, Andreas, Denk, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696705/
https://www.ncbi.nlm.nih.gov/pubmed/33202693
http://dx.doi.org/10.3390/ijms21228602