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IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is rising in prevalence, and a better pathophysiologic understanding of the transition to its inflammatory phenotype (NASH) is key to the development of effective therapies. To evaluate the contribution of the NLRP3 inflammasome and its downstream effectors...
Autores principales: | Hohenester, Simon, Kanitz, Veronika, Schiergens, Tobias, Einer, Claudia, Nagel, Jutta, Wimmer, Ralf, Reiter, Florian P., Gerbes, Alexander L., De Toni, Enrico N., Bauer, Christian, Holdt, Lesca, Mayr, Doris, Rust, Christian, Schnurr, Max, Zischka, Hans, Geier, Andreas, Denk, Gerald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696705/ https://www.ncbi.nlm.nih.gov/pubmed/33202693 http://dx.doi.org/10.3390/ijms21228602 |
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