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Antibacterial Effects of Bicarbonate in Media Modified to Mimic Cystic Fibrosis Sputum

Cystic fibrosis (CF) is a hereditary disease caused by mutations in the gene encoding an epithelial anion channel. In CF, Cl(−) and HCO(3)(−) hyposecretion, together with mucin hypersecretion, leads to airway dehydration and production of viscous mucus. This habitat is ideal for colonization by path...

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Detalles Bibliográficos
Autores principales: Jaikumpun, Pongsiri, Ruksakiet, Kasidid, Stercz, Balázs, Pállinger, Éva, Steward, Martin, Lohinai, Zsolt, Dobay, Orsolya, Zsembery, Ákos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696793/
https://www.ncbi.nlm.nih.gov/pubmed/33207565
http://dx.doi.org/10.3390/ijms21228614